Anisotrichosis in Female AGA

Variation in Follicular Caliber

Variation in size of follicles is typical of androgenetic alopecia (hereditary thinning). This has been termed "anisotrichosis." In this picture of a female patient with androgenetic hair loss, it can be seen that some hairs are thick and some are much thinner. The decrease in caliber is due in part to a decease in the size of the dermal papilla (a part of the hair follicle).

Reference
Sewell L et al Anisotrichosis: A novel term to describe pattern alopecia. J Am Acad Dermatol 2007; 56: 856.