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Ginger for Methotrexate related Nausea

Patients with autoimmune related hair loss, including those with alopecia areata and various scarring hair loss conditions may be prescribed methotrexate as one of their treatment options. Methotrexate is not typically a first line option but is an option for patients who don't respond to initial treatments

Methotrexate is taken once weekly. A trouble side effect is nausea. Several studies from cancer research field have started to explore whether extracts from ginger can be helpful to reduce nausea from cancer therapies. Ginger has been studied in other fields too - including studies addressing whether or not it can reduce nausea of pregnancy. 
Some studies, albeit not all, do support a benefit of ginger in reducing nausea. Many of our own hair loss patients who experience nausea when using methotrexate also feel some reduction in nausea with various ginger formulations including ginger candies.

More studies are need to determine the best doses and appropriate formulations. For now, I continue to follow the interesting research in the cancer field, and other fields, as to how to safely reduce nausea.


Dr. Jeff Donovan is a Canadian and US board certified dermatologist specializing exclusively in hair loss. To schedule a consultation, please call the Vancouver office at 604.283.9299



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