TREATMENT OPTIONS FOR GENETIC HAIR LOSS
Minoxidil and Finasteride are two FDA approved treatments for genetic hair loss. Other treatments like low level laser therapy (LLLT) and platelet rich plasma (PRP) are also possibilities.
What is PRP?
Platelet rich plasma is a treatment whereby a patient's own blood is used for treating his or her hair loss. We no longer live in a world where we wonder if PRP works. We have now entered an era where we have evidence it does something and now need to figure out how well it works and who it works in.
To date there have been approximately seven studies on the role of platelet rich plasma in treating genetic hair loss. These studies include:
1) Schiavone et al 2014
Number of patients in study: 64 patients
Design: PRP every 3 months
Results: At 6 months, 40.6% to 54.7 % had clinically significant change
2) Cervelli et al 2014
Number of patients in study: 10 patients
18 mL blood
Design: Randomized half head study
Results: Significant increase in terminal hairs at 3 months
3) Gkini MA et al
Number of patients in study: 20 patients
Design: 16 mL blood; 3 treatments q 21 days and at 6 months
Results: Hair increased; 7 out of 10 satisfaction rating
4) Park et al
Number of patients in study: 1 patient
Design: Weekly treatment x 4 week
Results: Hair grew faster
5) Kang JS et al
Number of patients in study: 13 patient
Design: One treatment
Results: Improved number of hairs and thickness
6) Khatu et al, 2014
Number of patients in study: 11 every
Design: 2 weeks x 4 treatments
Results: Improved thickness & hair counts by 22.09 FU per cm2
7) Betsi et al 2012
Number of patients in study: 42
Design: 16 mL blood
Results at 3 months; High patients satisfaction 7 of 10; Improvement in hair volume
Cervelli et al. The effect of autologous activated platelet rich plasma (AA-PRP) injection on pattern hair loss: clinical and histomorphometric evaluation. Biomed Res Int. 2014;2014:760709.
Gkini MA et al. Study of platelet-rich plasma injections in the treatment of androgenetic alopecia through an one-year period. J Cutan Aesthet Surg. 2014;7:213-9.
Kang JS et al . The effect of CD34+ cell-containing autologous platelet-rich plasma injection on pattern hair loss: a preliminary study. J Eur Acad Dermatol Venereol. 2014;28:72-9.
Khatu et al, Platelet-rich plasma in androgenic alopecia: myth or an effective tool. Cutan Aesthet Surg. 2014;7:107-10.
Park et al. Letter: Platelet-rich plasma for treating male pattern baldness. Dermatol Surg. 2012;38:2042-4.
Schiavone G et al. Platelet-rich plasma for androgenetic alopecia: a pilot study. Dermatol Surg. 2014;40:1010-9.
Dr. Jeff Donovan is a Canadian and US board certified dermatologist specializing exclusively in hair loss. To schedule a consultation, please call the Vancouver office at 604.283.9299