QUESTION: Does spironolactone cause hair loss?


Hair shedding from spironolactone is not common but can occur. Hair loss (if it occurs) usually it occurs within 3-4 months of starting the drug. In some cases it is a matter of weeks. Women on higher doses (100-200 mg) appear to have a higher risk than women on lower doses (25-100 mg)

I always advise seeing a dermatologist before concluding a drug is the cause of hair loss. Sometimes it's easy to sort out but often it's more challenging. All in all, hair loss is a fairly rare side effect of spironolactone - but it's certainly possible

Jeff Donovan MD PhD FRCPC FAAD
US & Canadian board-certified Dermatologist 
Toronto, Canada

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