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QUESTION OF THE WEEK


Systematic Review Highlights Risk Factors and Associations with Premature Greying of Hair

Systematic Review Captures Key Risks Associated with Early Greying of Hair

In 2020, Mahendiratta et al performed a systematic review to address factors associated with premature greying of hair.

Factors associated with premature greying of hair were : smoking, vitamin deficiency (B12, folic acid, and B7), mineral deficiency (low serum calcium and serum ferritin).

Other important risk factors are family history of PGH, obesity, high blood pressure, lack of exercise, drugs, genetic syndromes, dyslipidemia, thyroid disorders, hyperuricemia, and alteration in liver function.

In addition, premature greying was found to be an important marker of CAD, and this was increased further in the case of smokers.

REFERENCE

Mahendiratta S et al. Premature graying of hair: Risk factors, co-morbid conditions, pharmacotherapy and reversal-A systematic review and meta-analysis. Dermatol Ther. 2020 Nov;33(6):e13990.


This article was written by Dr. Jeff Donovan, a Canadian and US board certified dermatologist specializing exclusively in hair loss.



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